1. DE SOUZA, ANA CRISTINA ROCHA ; SANTANA, JEFERSON SANTOS ; KAMIKAWACHI, RENAN CANUTE ; MEIRELES, LEONARDO DIAS ; FERREIRA, MARCELO JOSÉ PENA ; de Castro Spadari, Cristina ; ISHIDA, KELLY ; SANNOMIYA, MIRIAM . Temporal analysis of extracts from the leaves of Eugenia uniflora L.: chemistry and antifungal activity. Brazilian Journal of Botany, v. 48, p. 35, 2025. DOI: https://doi.org/10.1007/s40415-025-01075-6

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2. DE OLIVEIRA MACEDO, LUIZA ; DA SILVA, ROSANA PEREIRA ; DE JESUS, DANIEL FELIPE FREITAS ; BRAGARD, ANDRÉ SAMPAIO ; DE ARAUJO, GABRIEL LIMA BARROS ; FERRAZ, HUMBERTO GOMES ; ISHIDA, KELLY ; BOU-CHACRA, NÁDIA ARACI . Firocoxib nanocrystals: Preparation, characterization, and pharmacokinetics in beagle dogs. INTERNATIONAL JOURNAL OF PHARMACEUTICS, v. x, p. 125756, 2025. DOI: https://doi.org/10.1016/j.ijpharm.2025.125756

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3. LYRA DE HOLANDA FONSECA, DOUGLAS ; SCHEUNEMANN, GABY SOARES ; FORTES, BRUNA NAKANISHI ; ISHIDA, KELLY ; GALHARDO, RODRIGO DA SILVA . Interaction of the SXT/R391 element ICE Pmi Jpn1 with its natural host Proteus mirabilis. MICROBIOLOGY SPECTRUM, v. x, p. e00339-25, 2025. DOI: 10.1128/spectrum.00339-25

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4. MACEDO, ANA BEATRIZ N. ; SILVA, DANIELE DE FIGUERÊDO ; MEDEIROS, ANTHONY G. J. ; FREITAS, GUSTAVO JOSÉ ; SANTOS, MURILO MOREIRA DOS ; ISHIDA, KELLY ; PERES, NALU TEIXEIRA DE AGUIAR ; SANTOS, DANIEL ASSIS ; ROSSATO, LUANA ; GOLDMAN, GUSTAVO H. ; BASTOS, RAFAEL WESLEY . Antagonistic effect of Pseudomonas aeruginosa on Candida auris. Frontiers In Fungal Biology, v. 6, p. 1613244, 2025. DOI: https://doi.org/10.3389/ffunb.2025.1613244

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5. SARTORE, M. H. ; LOPES, L. R. B. ; FERREIRA, M. J. P. ; SPADARI, CRISTINA C. ; ISHIDA, K. ; TANGERINA, M. M. P. ; NUNEZ, E. G. F. ; SANNOMIYA, M. . Antifungal profiling of Brazilian essential oils: Chemotype classification and correlation with bioactivity.. Acta Scientiarum. Technology (Online), v. 47, p. e71290, 2025.DOI: 10.4025/actascitechnol.v47i1.71290

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6. COSTA, NATHÁLIA EVELYN MORAIS ; BARRETO, THAYNÁ LOPES ; FREIRE, NATHALIA MONTEIRO LINS ; DA SILVA, JÚLIO COSME SANTOS ; AQUINO, THIAGO MENDONÇA DE ; ALBERTO, EDUARDO E. ; ISHIDA, KELLY ; DE FÁTIMA, ÂNGELO . Benzoylselenoureas: A Novel Dual-Action Inhibitor Targeting Fungal Growth and Urease Activity in Cryptococcus neoformans. ACS Omega, v. x, p. x, 2025.DOI: 10.1021/acsomega.5c06398

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7. MOREIRA DOS SANTOS, MURILO ; SANTOS MOURE, HENRIQUE ; FERREIRA, MARCELO JOSÉ PENA ; ISHIDA, KELLY . Do farnesol and tyrosol production in biofilms reflect virulence potential?. Virulence, v. x, p. x, 2025. DOI: 10.1080/21505594.2025.2561832

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8. TAVARES, ELIANDRO REIS ; SANTOS, VIRGINIA PREZZI ; CASTRO, ISABELA MADEIRA DE ; BORGES, PAULO HENRIQUE GUILHERME ; SILVA-RODRIGUES, GISLAINE ; OLAK, ANNA PAULA SILVA ; BARTOLOMEU-GONÇALVES, GUILHERME ; SANTOS, JUSSEVANIA PEREIRA ; MOREY, ALEXANDRE TADACHI ; ISHIDA, KELLY ; YAMADA-OGATTA, SUELI FUMIE ; YAMAUCHI, LUCY MEGUMI . Development of Melting-Curve-Based Real-Time PCR for Differentiating Medically Important Candida Species. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 26, p. 9411, 2025. DOI:https://doi.org/10.3390/ijms26199411

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9. ANDRÉS LIBREROS-ZÚÑIGA, GERARDO ; PAVÃO E PAVÃO, DANILO ; DE MORAIS BARROSO, VINICIUS ; CRISTINA DE MORAES ROSO MESQUITA, NATHALYA ; FEHELBERG PINTO BRAGA, SAULO ; OLIVA, GLAUCIUS ; SALGADO FERREIRA, RAFAELA ; ISHIDA, KELLY ; VINICIUS BERTACINE DIAS, MARCIO . Integration of biophysical and biological approaches to validate fragment-like compounds targeting l,d-transpeptidases from Mycobacterium tuberculosis. BIOORGANIC CHEMISTRY, v. 142, p. 106960, 2024. DOI: 10.1016/j.bioorg.2023.106960

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10. MIGUEL, RODRIGO DOS A. ; HIRATA, AMANDA S. ; SALATA, GIOVANNA C. ; APOLINÁRIO, ALEXSANDRA C. ; BARROSO, VINICIUS M. ; ISHIDA, KELLY ; LA CLAIR, JAMES J. ; FENICAL, WILLIAM ; MARTINS, TEREZA S. ; COSTA-LOTUFO, LETICIA V. ; LOPES, LUCIANA B. Topical delivery of seriniquinone for treatment of skin cancer and fungal infections is enabled by a liquid crystalline lamellar phase. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, v. 192, p. 106635, 2024. DOI: 10.1016/j.ejps.2023.106635

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11. MASIERO, JÉSSICA FAGIONATO ; KNIRSCH, MARCOS CAMARGO ; BARRETO, THAYNÁ ; ARANTES, GERALDO JOSÉ ; STEPHANO, MARCO ANTONIO ; ISHIDA, KELLY ; LOBËNBERG, RAIMAR ; BOU-CHACRA, NÁDIA ARACI . Unveiling the optimal path: High-pressure homogenization and D-phase emulsification methods for borage oil nanoemulsion design. INDUSTRIAL CROPS AND PRODUCTS, v. 208, p. 117853, 2024. DOI:https://doi.org/10.1016/j.indcrop.2023.117853

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12. PASSOS, JULIA S. ; APOLINARIO, ALEXSANDRA C. ; ISHIDA, KELLY ; MARTINS, TEREZA S. ; LOPES, LUCIANA B. . Nanostructured lipid carriers loaded into in situ gels for breast cancer local treatment. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, v. 192, p. 106638, 2024. DOI: 10.1016/j.ejps.2023.106638

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13. RODRIGUES, CLENILSON MARTINS ; BENTO, CHARLYANA CARVALHO ; MORAES, CAROLINA BORSOI ; GOMES, CECILIA ; IOSHINO, RAFAELLA SAYURI ; FREITAS-JUNIOR, LUCIO H. ; DE CASTRO SPADARI, CRISTINA; ISHIDA, KELLY ; VILEGAS, WAGNER ; CARVALHO, JULIANA CAJADO SOUZA ; FERREIRA, MARCELO JOSÉ PENA ; CARBONE, VIRGINIA ; PIACENTE, SONIA ; MOLINA DE ANGELO, RAFAELA ; HONORIO, KATHIA MARIA ; SANNOMIYA, MIRIAM . A potential antiviral against COVID-19 obtained from Byrsonima coccolobifolia leaves extract. FITOTERAPIA, v. 173, p. 105820, 2024. DOI: 10.1016/j.fitote.2024.105820

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14. DOURADO, CAMILA PINTO ; KAMIKAWACHI, RENAN CANUTE ; FERREIRA, MARCELO JOSÉ PENA ; SARTORI, ÂNGELA LÚCIA BAGNATORI ; RODRIGUES, CLENILSON MARTINS ; SPADARI, CRISTINA DE CASTRO ; ISHIDA, KELLY ; SANNOMIYA, MIRIAM . Exploring antifungal potential: The flavonoid composition of Machaerium villosum extracts against Cryptococcus neoformans. RESEARCH, SOCIETY AND DEVELOPMENT, v. 13, p. e1613144604, 2024. DOI: https://doi.org/10.33448/rsd-v13i1.44604

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15. BARROSO, VINÍCIUS M. ; REIS, JOEL S. ; STEFANI, HÉLIO A. ; ISHIDA, KELLY. 2-aryloxazolines inhibit Candida clinical isolates growth and morphogenesis of Candida albicans and Candida tropicalis. The Microbe, v. 3, p. 100062, 2024. DOI: https://doi.org/10.1016/j.microb.2024.100062

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16. FORTES, BRUNA NAKANISHI ; WIRTH, FERNANDA ; DOS SANTOS, ALINE MARTINS ; CHORILLI, MARLUS ; FREITAS, VANESSA MORAIS ; FARIAS, JENNIFER ; CHAMBERGO, FELIPE S ; NUNES C DANTAS, VIVIANE ABREU ; ISHIDA, KELLY . Three-dimensional lung parenchyma model for studies of Aspergillus fumigatus infection and antifungal treatment. Future Microbiology, v. x, p. 1-14, 2024. DOI: 10.1080/17460913.2024.2371926

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17. BARBOSA, EDUARDO JOSÉ ; FUKUMORI, CLAUDIO ; DE ARAÚJO SPRENGEL, SARAH ; BARRETO, THAYNÁ LOPES ; ISHIDA, KELLY ; DE ARAUJO, GABRIEL LIMA BARROS ; BOU-CHACRA, NÁDIA ARACI ; LOPES, LUCIANA BIAGINI . Niclosamide nanoemulsion for colorectal cancer: development, physicochemical characterization, and in vitro anticancer activity. JOURNAL OF NANOPARTICLE RESEARCH, v. 26, p. 221, 2024. DOI: https://doi.org/10.1007/s11051-024-06126-9

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18. MARTINS, LAYLA FARAGE ; DOS SANTOS JUNIOR, ARIOSVALDO PEREIRA ; NICASTRO, GIANLUCCA GONÇALVES ; SCHEUNEMANN, GABY ; ANGELI, CLAUDIA BLANES ; ROSSI, FERNANDO PACHECO NOBRE ; QUAGGIO, RONALDO BENTO ; PALMISANO, GIUSEPPE ; SGRO, GERMÁN GUSTAVO ; ISHIDA, KELLY ; BALDINI, REGINA LÚCIA ; DA SILVA, ALINE MARIA . Phages ZC01 and ZC03 require type-IV pilus for infection and have a potential for therapeutic applications. MICROBIOLOGY SPECTRUM, v. x, p. e01527-24, 2024. DOI: 10.1128/spectrum.01527-24

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19. SILVA-RODRIGUES, GISLAINE ; CASTRO, ISABELA MADEIRA DE ; BORGES, PAULO HENRIQUE GUILHERME ; SUZUKAWA, HELENA TIEMI ; SOUZA, JOYCE MARINHO DE ; BARTOLOMEU-GONÇALVES, GUILHERME ; PELISSON, MARSILENI ; MEDEIROS, CÁSSIO ILAN SOARES ; BISPO, MARCELLE DE LIMA FERREIRA ; ALMEIDA, RICARDO SÉRGIO COUTO DE ; ISHIDA, KELLY ; TAVARES, ELIANDRO REIS ; YAMAUCHI, LUCY MEGUMI ; YAMADA-OGATTA, SUELI FUMIE . Geraniol Potentiates the Effect of Fluconazole against Planktonic and Sessile Cells of Azole-Resistant Candida tropicalis: In Vitro and In Vivo Analyses. PHARMACEUTICS, v. 16, p. 1053, 2024. DOI: 10.3390/pharmaceutics16081053

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20. AREDES DA ROCHA, NATALY ; DE SOUZA, ALINE ; NISHITANI YUKUYAMA, MEGUMI ; LOPES BARRETO, THAYNA ; DE O. MACEDO, LUIZA ; LÖBENBERG, RAIMAR ; LIMA BARROS DE ARAÚJO, GABRIEL ; ISHIDA, KELLY ; ARACI BOU-CHACRA, NÁDIA . Highly water-soluble dapsone nanocrystals: Towards innovative preparations for an undermined drug. INTERNATIONAL JOURNAL OF PHARMACEUTICS, v. 630, p. 122428, 2023. DOI: 10.1016/j.ijpharm.2022.122428

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21. FORTES, BRUNA NAKANISHI ; SCHEUNEMANN, GABY ; DE AZEVEDO MELO, ANALY SALLES ; ISHIDA, KELLY. Caspofungin alone or combined with polymyxin B are effective against mixed biofilm of Aspergillus fumigatus and carbapenem-resistant Pseudomonas aeruginosa. RESEARCH IN MICROBIOLOGY, v. 174, p. 103993, 2023. DOI: 10.1016/j.resmic.2022.103993

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22. JESUS, D. F. F. ; FREITAS, A. L. D. ; SPADARI, C. C. ; OLIVEIRA, I. M. ; ALMEIDA, L. C. ; MELO, A. S. A. ; SANTOS, D.A. ; BASTOS, R. W. ; COSTA-LOTUFO, L. V. ; REIS, F. C. G. ; RODRIGUES, M. L. ; STEFANI, H. A. ; ISHIDA, K.  Organoselenium Has a Potent Fungicidal Effect on Cryptococcus neoformans and Inhibits the Virulence Factors. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, p. e00759-22, 2023. DOI: 10.1128/aac.00759-22

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23. SPADARI, CRISTINA C. ; LANSER, D. M. ; ARAUJO, M. V. ; JESUS, D. F. F. ; LOPES, L.B. ; GELLI, A. ; ISHIDA, K. Oral delivery of brain-targeted miltefosine-loaded alginate nanoparticles functionalized with polysorbate 80 for the treatment of cryptococcal meningitis. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, p. 1092-1101, 2023. DOI: 10.1093/jac/dkad053

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24. SPOLADORI, L. F. A. ; ANDRIANI, G. M. ; CASTRO, I. M. ; SUZUKAWA, H. T. ; GIMENES, A. C. R. ; BARTOLOMEU-GONCALVES, G. ; ISHIDA, K. ; NAKAZATO, G. ; PINGE-FILHO, P. ; MACHADO, R. R. B. ; NAKAMURA, C. V. ; ANDRADE, G. ; TAVARES, E. R. ; YAMAUCHI, L. M. ; YAMADA-OGATTA, S. F.  Synergistic Antifungal Interaction between Pseudomonas aeruginosa LV Strain Metabolites and Biogenic Silver Nanoparticles against Candida auris. ANTIBIOTICS-BASEL, v. 12, p. 861, 2023. DOI: 10.3390/antibiotics12050861

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25. FUKUMORI, C. ; BRANCO, P. C. ; BARRETO, T. L. ; ISHIDA, K. ; LOPES, L.B.  Development and cytotoxicity evaluation of multiple nanoemulsions for oral co-delivery of 5-fluorouracil and short chain triglycerides for colorectal cancer. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, v. 187, p. 106465, 2023. DOI: 10.1016/j.ejps.2023.106465

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26. KIRKMAN, TIM ; SKETCHER, ALICE ; DE MORAIS BARROSO, VINICIUS ; ISHIDA, KELLY ; TOSIN, MANUELA ; DIAS, MARCIO VINICIUS BERTACINE . Crystal structure of dihydrofolate reductase from the emerging pathogenic fungus Candida auris. Acta Crystallographica Section D-Structural Biology, v. 79, p. 1-11, 2023. DOI: 10.1107/S2059798323004709

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27. SANTOS-LIMA, D. ; SPADARI, C. C. ; BARROSO, V. M. ; CARVALHO, J. C. S. ; ALMEIDA, L. C. ; ALCALDE, F. S. C. ; FERREIRA, M. J. P. ; SANNOMIYA, M. ; ISHIDA, K. Lipopeptides from an isolate of Bacillus subtilis complex have inhibitory and antibiofilm effects on Fusarium solani. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, v. 107, p. 6103-6120, 2023. DOI: 10.1007/s00253-023-12712-z

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28. DOS SANTOS, MURILO MOREIRA ; ISHIDA, KELLY . We need to talk about Candida tropicalis : Virulence factors and survival mechanisms. MEDICAL MYCOLOGY, v. 61, p. myad075, 2023. DOI: 10.1093/mmy/myad075

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29. PORTES, R. G. ; BARRETO, THAYNÁ LOPES ; KANEMARU, MICHEL YUDI SHINKAI ; ISHIDA, KELLY ; BICAS, JULIANO LEMOS.  Antifungal activity of cercosporamide produced by Phaeosphaeriaceae GV-1 against pathogenic fungi. BRAZILIAN JOURNAL OF MICROBIOLOGY, v. x, p. x, 2023. DOI: 10.1007/s42770-023-01211-y

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30. SPADARI, CRISTINA DE CASTRO ; BORBA-SANTOS, LUANA PEREIRA ; ROZENTAL, SONIA ; ISHIDA, KELLY . Miltefosine repositioning: A review of potential alternative antifungal therapy. JOURNAL DE MYCOLOGIE MEDICALE, v. 33, p. 101436, 2023. DOI: 10.1016/j.mycmed.2023.101436

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31. VIANELLO, M. ; JESUS, D. F. F. ; SAMPAIO, J. ; OLIVEIRdA, G. M. ; LINCOPAN, N ; ISHIDA, K. . Possible Trichosporon asahii urinary tract infection in a critically ill COVID-19 patient. REVISTA IBEROAMERICANA DE MICOLOGIA, v. 39, p. 54-56, 2022. DOI: 10.1016/j.riam.2022.05.001

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32. SPADARI, CRISTINA DE CASTRO ; BARRETO, THAYNÁ LOPES ; DE QUEIROZ, VAGNER TEBALDI ; DE PAIVA, WALYSSON FERREIRA ; FERNANDES, SERGIO ANTONIO ; DE FÁTIMA, ÂNGELO ; ISHIDA, KELLY . Ketoconazole/calix[n]arenes-based compounds improve the antifungal activity against azole-resistant Candida isolates. JOURNAL DE MYCOLOGIE MEDICALE, v. 32, p. 101254, 2022. DOI: 10.1016/j.mycmed.2022.101254

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33. SANNOMIYA, MIRIAM ; RODRIGUES, CLENILSON MARTINS ; OLIVEIRA, GIOVANNA CASTRO ARAÚJO ; CARVALHO, JULIANA CAJADO SOUZA; DA COSTA, LETÍCIA SERAFIM ; SPADARI, CRISTINA DE CASTRO ; FERREIRA, MARCELO JOSÉ PENA ; VILEGAS, WAGNER ; ISHIDA, KELLY . Galloylquinic acid derivatives from Byrsonima fagifolia leaf extract and potential antifungal activity. JOURNAL OF ETHNOPHARMACOLOGY, v. 297, p. 115534, 2022. DOI: https://doi.org/10.1016/j.jep.2022.115534

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34. JESUS, JOSÉ IZO SANTANA DA SILVA DE ; LOURENÇO, FELIPE REBELLO ; ISHIDA, KELLY ; BARRETO, THAYNÁ LOPES ; AVINO, VALDIR CARLOS ; NETO, EDSON DOS SANTOS ; BOU-CHACRA, NÁDIA ARACI . Besifloxacin Nanocrystal: Towards an Innovative Ophthalmic Preparation. PHARMACEUTICS, v. 14, p. 2221, 2022. DOI: 10.3390/pharmaceutics14102221

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35. WIRTH, FERNANDA ; STAUDT, KELI J ; ARAÚJO, BIBIANA V ; ISHIDA, KELLY . Experimental models for pharmacokinetic and pharmacodynamic studies of antifungals used in cryptococcosis treatment. Future Microbiology, v. 17, p. 969-982, 2022. DOI: 10.2217/fmb-2021-0291

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36. BARRETO, T. L. ; LOPES, L.B. ; MELO, A. S. A. ; ISHIDA, K. In vivo synergism of free miltefosine or in alginate-based nanocarrier combined with voriconazole on aspergillosis. Future Microbiology, v. 16, p. 1153-1160, 2021. DOI: 10.2217/fmb-2021-0056

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37. BORBA-SANTOS, LUANA PEREIRA ; BARRETO, THAYNÁ LOPES ; VILA TAISSA ; CHI, KUNG DARH ; DOS SANTOS MONTI, FABIANA ; DE FARIAS, MARCONI RODRIGUES ; ALVIANO, DANIELA S. ; ALVIANO, CELUTA S. ; FUTURO, DÉBORA O. ; FERREIRA, VITOR ; de Souza, Wanderley ; ISHIDA, KELLY ; Rozental, Sonia . In Vitro and In Vivo Antifungal Activity of Buparvaquone against Sporothrix brasiliensis. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, v. 65, p. e0069921, 2021. DOI: 10.1128/AAC.00699-21

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38. YUKUYAMA, M. N. ; ISHIDA, K. ; ARAUJO, G. L. B. ; SPADARI, C. C. ; SOUZA, A. ; LOBENBERG, R. ; HENOSTROZA, M. A. B. ; FOLCHINI, B. R. ; PERONI, C. M. ; PETERS, M. C. C. ; OLIVEIRA, I. F. ; MIYAGI, M. Y. S. ; BOU-CHACRA, N. A. Rational design of oral flubendazole-loaded nanoemulsion for brain delivery in cryptococcosis. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, v. 630, p. 127631, 2021. DOI: https://doi.org/10.1016/j.colsurfa.2021.127631

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39. SCHEUNEMANN, G. ; FORTES, B.N. ; LINCOPAN, N. ; ISHIDA, K. Caspofungin inhibits mixed biofilms of Candida albicans and methicillin-resistant Staphylococcus aureus and displays effectiveness in coinfected Galleria mellonella larvae. MICROBIOLOGY SPECTRUM, v. 9, p. e00744-21, 2021. DOI: 10.1128/Spectrum.00744-21

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40. COSTA-FERNANDEZ, SANDRA ; MATOS, JENYFFER K.R. ; SCHEUNEMANN, GABY S. ; SALATA, GIOVANNA C. ; CHORILLI, MARLUS ; WATANABE, IL-SEI ; DE ARAUJO, GABRIEL L.B. ; SANTOS, MARINILCE F. ; ISHIDA, KELLY ; LOPES, LUCIANA B.  Nanostructured lipid carriers containing chitosan or sodium alginate for co-encapsulation of antioxidants and an antimicrobial agent for potential application in wound healing. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, v. 183, p. 668-680, 2021. DOI: 10.1016/j.ijbiomac.2021.04.168

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41. BASTIANI, F. W. M. S. ; SPADARI, C.C. ; DE MATOS, J.K.R. ; SALATA, G. C. ; LOPES, L.B. ; ISHIDA, K. Nanocarriers provide sustained antifungal activity in the topical treatment of murine vaginal candidiasis. Frontiers in Microbiology, v. 10, p. 2976, 2020. DOI: 10.3389/fmicb.2019.02976

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42. SPADARI, C.C. ; BASTIANI, F. W. M. S. ; PISANI, P. B.B. ; MELO, A. S. A. ; ISHIDA, K. Efficacy of voriconazole in vitro and in invertebrate model of cryptococcosis. ARCHIVES OF MICROBIOLOGY, v. 202, p. 773-784, 2020. DOI: 10.1007/s00203-019-01789-8

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43. PASSOS, JULIA SAPIENZA ; MARTINO, LUIZA CAPELLO DE ; DARTORA, VANESSA FRANCO CARVALHO; ARAUJO, GABRIEL L. B. DE ; ISHIDA, KELLY ; LOPES, LUCIANA B. Development, Skin Targeting And Antifungal Efficacy Of Topical Lipid Nanoparticles Containing Itraconazole. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, v. 3, p. 105296-105296, 2020. DOI: https://doi.org/10.1016/j.ejps.2020.105296

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44. SPADARI, C.C. ; WIRTH, F. ; LOPES, L.B. ; ISHIDA, K. New approaches for cryptococcosis treatment. Microorganisms, v. 8, p. 613, 2020. DOI: 10.3390/microorganisms8040613

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45. BARRETO, THAYNÁ LOPES ; ROSSATO, LUANA ; DE FREITAS, ALINE LUIZA DUARTE ; MEIS, JACQUES F. ; LOPES, LUCIANA BIAGINI ; COLOMBO, ARNALDO LOPES ; ISHIDA, KELLY . Miltefosine as an alternative strategy in the treatment of the emerging fungus Candida auris. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, v. 56, p. 106049, 2020. DOI: 10.1016/j.ijantimicag.2020.106049

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46. ROSSATO, LUANA ; DOS SANTOS, MARIELLE CAMARGO ; VITALE, ROXANA G. ; DE HOOG, SYBREN ; ISHIDA, KELLY. Alternative treatment of fungal infections: synergy with non¿antifungal agents. MYCOSES, v. 00, p. 1-13, 2020. DOI: 10.1111/myc.13203

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47. ARGOMEDO, L. M. Z. ; BARROSO, V. M. ; BARREIRO, C. S. ; DARBEM, M. P. ; STEFANI, H. A. ; ISHIDA, K. Novel 2-Aryloxazoline Compounds Exhibit an Inhibitory Effect on Candida spp., Including Antifungal-Resistant Isolates. ACS Medicinal Chemistry Letters, v. 11, p. 2470-2475, 2020. DOI: 10.1021/acsmedchemlett.0c00449

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48. FERNANDES, L. ; FORTES, B.N. ; LINCOPAN, N ; ISHIDA, K. Caspofungin and polymyxin B reduce the cell viability and total biomass of mixed biofilms of carbapenem-resistant Pseudomonas aeruginosa and Candida spp.. Frontiers in Microbiology, v. 11, p. 573263, 2020. DOI:https://doi.org/10.3389/fmicb.2020.573263

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49. WIRTH, FERNANDA ; ISHIDA, KELLY. Antifungal drugs: An updated review of central nervous system pharmacokinetics. MYCOSES, v. 63, p. 1047-1059, 2020. DOI: 10.1111/myc.13157

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50. ​SPADARI, CRISTINA DE CASTRO ; DE BASTIANI, FERNANDA WALT MENDES DA SILVA ; LOPES, LUCIANA BIAGINI ; ISHIDA, KELLY.

Alginate nanoparticles as non-toxic delivery system for miltefosine in the treatment of candidiasis and cryptococcosis. International Journal of Nanomedicine, v. Volume 14, p. 5187-5199, 2019. DOI: 10.2147/IJN.S205350

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51. FREITAS, A.L.D.; KAPLUM, V.; ROSSI, D.C.P.; DA SILVA, L.B.R.; MELHEM, M.S.C.; TABORDA, C.P.; MELLO, J.C.P.; NAKAMURA, C.V.; ISHIDA, K. Proanthocyanidin polymeric tannins from Stryphnodendron adstringens are effective against Candida spp. isolates and for vaginal candidiasis treatment. Journal of Ethnopharmacology, v. 216, p. 184–190, 2018. DOI: 10.1016/j.jep.2018.01.008

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31. MIGOTTO, A.; CARVALHO, V. F.M.; SALATA, G.; DA SILVA, F. W. M.; YAN, C. Y. I.; ISHIDA, K.; COSTA-LOTUFO, L.; STEINER, A.A.; LOPES, L.B. Multifunctional nanoemulsions for intraductal delivery as a new platform for treatment of breast cancer. Drug Delivery, 2018. DOI: 10.1080/10717544.2018.1440665

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30. ROSSI, D. C. P.; SPADARI, C.C.; NOSANCHUCK, J. D.; TABORDA, C. P.; ISHIDA, K. Miltefosine is fungicidal to Paracoccidioides spp. yeast cells but sub- inhibitory concentrations induce melanization. International Journal of Antimicrobial Agents (Print), v.49, p.465 - 471, 2017. DOI: 10.1016/j.ijantimicag.2016.12.020

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29. SPADARI, CRISTINA DE CASTRO; LOPES, LUCIANA B.; ISHIDA, KELLY. Potential Use of Alginate-Based Carriers As Antifungal Delivery System. Frontiers in Microbiology (Online), v.8, p.1 - 11, 2017. DOI: 10.3389/fmicb.2017.00097

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28. ISHIDA, K.; CASTRO, R. A.; TORRADO, J. J.; SERRANO, D. R.; BORBA-SANTOS, L. P.; QUINTELA, L. P.; DE SOUZA, W.; ROZENTAL, S.; LOPES-BEZERRA, L. M. Efficacy of a poly-aggregated formulation of amphotericin B in treating systemic sporotrichosis caused by Sporothrix brasiliensis. MEDICAL MYCOLOGY, myx040, 2017. DOI: 10.1093/mmy/myx040

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27. VILA, T.V.M.; FONSECA, B.B.; CUNHA, M.M.L.; SANTOS, G. R. C.; ISHIDA, KELLY; BERGTER, E. B.; DE SOUZA, W.; ROZENTAL, S. Candida albicans biofilms: comparative analysis of room-temperature and cryo-fixation for scanning electron microscopy. Journal of Microscopy, 2017. DOI: 10.1111/jmi.12580

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26. MUÑOZ, JULIAN E.; ROSSI, DIEGO C. P.; ISHIDA, KELLY; SPADARI, CRISTINA C.; MELHEM, MARCIA S. C.; GARCIA, DANIEL M.; CAIRES, ANTONIO C. F.; TABORDA, CARLOS P.; RODRIGUES, ELAINE G. Antifungal Activity of the Biphosphinic Cyclopalladate C7a against Candida albicans Yeast Forms In Vitro and In Vivo. Frontiers in Microbiology, v.8, p.1 - 10, 2017. DOI: https://doi.org/10.3389/fmicb.2017.00771

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25. BONILLA JJA; GUERRERO, DJP; SUAREZ CIS; SAEZ, RGT; ISHIDA, K.; FONSECA, BB; ROZENTAL, S.; LOPEZ, CCO. Green synthesis of silver nanoparticles using maltose and cysteine and their effect on cell wall envelope shapes and microbial growth of Candida spp. Journal of Nanoscience and Nanotechnology (Print), v.17, p. 1729 - 1739, 2017. DOI: https://doi.org/10.1166/jnn.2017.12822

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24. BORBA-SANTOS, L. P.; ISHIDA, K.; CALOGEROPOULOU, T.; DE SOUZA, W.; ROZENTAL, S. Adamantylidene-substituted alkylphosphocholine TCAN26 is more active against Sporothrix schenckii than miltefosine. Memórias do Instituto Oswaldo Cruz (Online), p.1 - 5, 2016.  DOI: https://doi.org/10.1590/0074-02760160088

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23. BOATTO, H. F.; CAVALCANTI, S. D. B.; DEL NEGRO, G. M. B.; GIRAO, M. J. B. C.; FRANCISCO, E. C.; ISHIDA, K.; GOMPERTZ, O. F. Candida duobushaemulonii: an emerging rare pathogenic yeast isolated from recurrent vulvovaginal candidiasis in Brazil. Memórias do Instituto Oswaldo Cruz (Online), v.111, p.407 - 410, 2016. DOI: 10.1590/0074-02760160166

 

22. BORBA-SANTOS, L. P.; VISBAL, G.; BRAGA TG; RODRIGUES, A. M.; CAMARGO, Z. P.; LOPES- BEZERRA, L.M.; ISHIDA, K.; SOUZA, W.; ROZENTAL, S. Inhibition of Delta-24-sterol methyltransferase reduces growth of Sporothrix schenckii and Sporothrix brasiliensis. Frontiers in Microbiology (Online). , v.7, p.1 - 13, 2016. DOI: https://doi.org/10.3389/fmicb.2016.00311

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21. VILA, T. V. M.; ISHIDA, K.; SEABRA, S. H.; ROZENTAL, S. Miltefosine inhibits Candida albicans and non-albicans Candida spp. biofilms and impairs the dispersion of infectious cells. International Journal of Antimicrobial Agents (Print). , v.48, p.512 - 520, 2016. DOI: 10.1016/j.ijantimicag.2016.07.022

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20. LUIZ, R. L. F.; VILA, T.V.M.; MELLO, J. C. P.; NAKAMURA, C. V.; ROZENTAL, S.; ISHIDA, K. Proanthocyanidins polymeric tannin from Stryphnodendron adstringens are active against Candida albicans biofilms. BMC Complementary and Alternative Medicine (Online), v. 15, p. 68-78, 2015. DOI: 10.1186/s12906-015-0597-4

 

19. BORBA-SANTOS, L. P.; GAGINI, T.; ISHIDA, K.; DE SOUZA, W.; ROZENTAL, S. Miltefosine is active against Sporothrix brasiliensis isolates with in vitro low susceptibility to amphotericin B or itraconazole. Journal of Medical Microbiology, v. Fev, p. 1, 2015. DOI: 10.1099/jmm.0.000041

 

18. ISHIDA, K. ; CASTRO, R. A. ; SANTOS, L. P. B. ; QUINTELLA, L. ; LOPES-BEZERRA, L.M. ; ROZENTAL, S. Amphotericin B, alone or followed by itraconazole therapy, is effective in the control of experimental disseminated sporotrichosis by Sporothrix brasiliensis. Medical Mycology (Oxford. Print), v. 53, p. 34-41, 2015. DOI: 10.1093/mmy/myu050

 

17. BORBA-SANTOS, L. P. ; RODRIGUES, A. M. ; GAGINI, T. B. ; FERNANDES, G. F. ; CASTRO, R. ; DE CAMARGO, Z. P. ; NUCCI, M. ; LOPES-BEZERRA, L. M. ; ISHIDA, K. ; ROZENTAL, S. Susceptibility of Sporothrix brasiliensis isolates to amphotericin B, azoles, and terbinafine. Medical Mycology (Oxford. Online), v. 53, p. 178-188, 2015. DOI: https://doi.org/10.1093/mmy/myu056

 

16. ISHIDA, K. ; CIPRIANO T ; ROCHA, G.M. ; WEISSMÜLLER, G. ; GOMES, F. ; MIRANDA, K. ; ROZENTAL, S. Silver nanoparticle production by the fungus Fusarium oxysporum: nanoparticle characterisation and analysis of antifungal activity against pathogenic yeasts. Memórias do Instituto Oswaldo Cruz (Impresso), v. 108, p. 1-9, 2014. DOI: 10.1590/0074-0276130269

 

15. VILA, T. V. M. ; ISHIDA, K. ; DE SOUZA, W. ; PROUSIS, K. ; CALOGEROPOULOU, T. ; ROZENTAL, S. Effect of alkylphospholipids on Candida albicans biofilm formation and maturation. Journal of Antimicrobial Chemotherapy (Online), v. 68, p. 113-125, 2013. DOI: 10.1093/jac/dks353

 

14. ISHIDA, K. ; UEDA-YAMAGUCHI, M. ; YYAMADA-OGATTA, S.F. ; UEDA-NAKAMURA, T. ; SVIDZINSKI, T.I.E. ; NAKAMURA, C. V. . Characterization of Candida spp. isolated from vaginal fluid: identification, antifungal susceptibility, and virulence profile. Acta Scientiarum. Health Sciences (Online), v. 35, p. 1-8, 2013. DOI: https://doi.org/10.4025/actascihealthsci.v35i1.13557

 

13. ISHIDA, K., UEDA-YAMAGUCHI, M., UEDA-NAKAMURA, T., DIAS FILHO, B. P., YYAMADA-OGATTA, S.F., NAKAMURA, C. V. Performance of methods for identification of yeasts isolated from blotted water: High prevalence of Candida parapsilosis. Semina. Ciências Biológicas e da Saúde (Online), v.34, p.205-214, 2013.

 

12. COTTA SR ; MOTA FF ; TUPINAMBÁ G ; ISHIDA, K. ; ROZENTAL, S. ; SILVA, D.O. ; SILVA, A.J.R. ; ALVIANO, D. S. ; SELDIN, L. . Antimicrobial activity of Paenibacillus kribbensis POC 115 against the dermatophyte Trichophyton rubrum. World Journal of Microbiology & Biotechnology Incorporating the MIRCEN Journal of Applied Microbiology and Biotechnology (Dordrecht. Online), v. 28, p. 953-962, 2012. DOI: 10.1007/s11274-011-0893-1

 

11. GUERRA, C. R. ; ISHIDA, K. ; NUCCI, M.L.M. ; ROZENTAL, S.  Terbinafine inhibits Cryptococcus neoformans growth and modulates fungal morphology. Memórias do Instituto Oswaldo Cruz (Impresso), v. 107, p. 582-590, 2012. DOI:  https://doi.org/10.1590/S0074-02762012000500003 

 

10. ISHIDA, K. ; ALVIANO, D. S. ; SILVA, B.G. ; GUERRA, C. R. ; COSTA, A. S. ; NUCCI, M.L.M. ; ALVIANO, C.S. ; ROZENTAL, S. Negative correlation between phospholipase and esterase activity produced by Fusarium isolates. Brazilian Journal of Medical and Biological Research on line, v. 45, p. 411-416, 2012. DOI: 10.1590/s0100-879x2012007500034

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9. ISHIDA, K. ; VISBAL, G. ; RODRIGUES, J. C. F. ; URBINA, J.A. ; SOUZA, W. ; ROZENTAL, S. Two squalene synthase inhibitors, E5700 and ER-119884, interfere with cellular proliferation and induce ultrastructural and lipid profile alterations in a Candida tropicalis strain resistant to fluconazole, itraconazole and amphotericin B. Journal of Infection and Chemotherapy, v. 17, p. 563-570, 2011. DOI: 10.1007/s10156-010-0190-1

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8. ISHIDA, K. ; RODRIGUES, J. C. F. ; CAMMERER, S. ; URBINA, J.A. ; GILBERT, I. ; SOUZA, W. ; ROZENTAL, S. Synthetic arylquinuclidine derivatives exhibit antifungal activity against Candida albicans, Candida tropicalis and Candida parapsilopsis. Annals of Clinical Microbiology and Antimicrobials, v. 10, p. 3-12, 2011. DOI: 10.1186/1476-0711-10-3

 

7. COSTA, MA ; ISHIDA, K. ; BRAGA, C. F. S. ; KAPLUM, V. ; KOSLYK, EDA ; Mello, J C P ; NAKAMURA, T. U. ; DIAS FILHO, B. P. ; NAKAMURA, C. V. . Safety evaluation of proanthocyanidin polymer-rich fraction obtained from stem bark of Stryphnodendron adstringens (BARBATIMÃO) for use as a pharmacological agent. Regulatory Toxicology and Pharmacology, v. xx, p. x-x, 2010. DOI: 10.1016/j.yrtph.2010.07.006

 

6. ISHIDA, K. ; RODRIGUES, J. C. F. ; RIBEIRO, M.D. ; VILA, T. ; SOUZA, W. ; URBINA, J.A. ; NAKAMURA, C. V. ; ROZENTAL, S. . Growth inhibition and ultrastructural alterations induced by Δ24(25)-sterol methyltransferase inhibitors in Candida spp. isolates, including non-albicans organisms. BMC Microbiology (Online), v. 9, p. 74-85, 2009. DOI: 10.1186/1471-2180-9-74

 

5. ISHIDA, K. ; ROZENTAL, S. ; MELLO, J C P ; NAKAMURA, C. V. . Activity of tannins from Stryphnodendron adstringens on Cryptococcus neoformans: effects on growth, capsule size and pigmentation. Annals of Clinical Microbiology and Antimicrobials, v. 8, p. 29-38, 2009. DOI:  10.1186/1476-0711-8-29

 

4. MUSIAL, D. C. ; OLIVEIRA, J. E. ; LIMA, E. L. W. ; ISHIDA, K. ; SCOARIS, D. O. . Frequência de leveduras em exames colpocitológicos oferecidos pelo SUS em duas cidades do norte paranaense. Revista de Biologia e Saúde da UNISEP, v. 4, p. 1-5, 2009.

 

3. OBICI, S. ; OCTOBONE, F.J. ; SELA, V. R. S. ; ISHIDA, K. ; SILVA, J.C. ; NAKAMURA, C. V. ; CORTEZ, D. A. G. ; AUDI, E.A. . Preliminary toxicity study of dichloromethane extract of Kielmeyera coriacea stems in mice and rats. Journal of Ethnopharmacology, v. 115, p. 131-139, 2008. DOI: 10.1016/j.jep.2007.09.013

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 2. ISHIDA, K. ; MELLO, J C P ; CORTEZ, D. A. G. ; DIAS FILHO, B. P. ; NAKAMURA, T. U. ; NAKAMURA, C. V. . Influence of tannins from Stryphnodendron adstringens on growth and virulence factors of Candida albicans. Journal of Antimicrobial Chemotherapy (Print), v. 58, p. 942-949, 2006. DOI: 10.1093/jac/dkl377

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1. NAKAMURA, C. V. ; ISHIDA, K. ; FACCIN, L. C. ; DIAS FILHO, B. P. ; CORTEZ, D. A. G. ; ROZENTAL, S. ; SOUZA, W. ; NAKAMURA, T. U. . In vitro activity of essential oil of Ocimum gratissimum L. against four Candida species. Research in Microbiology (Paris), Holanda, v. 155, n.7, p. 579-586, 2004. DOI: 10.1016/j.resmic.2004.04.004

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